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Detection of Citrullinated Fibrin in Plasma Clots of Rheumatoid Arthritis Patients and Its Relation to Altered Structural Clot Properties, Disease-Related Inflammation and Prothrombotic Tendency

AIMS: The risk of cardiovascular events in patients with Rheumatoid Arthritis (RA) is disproportionately heightened as a result of systemic inflammation. The relative effect of autoimmune-associated citrullination on the structure and thrombotic potential of fibrin(ogen) remains unknown. We therefor...

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Udgivet i:Front Immunol
Main Authors: Bezuidenhout, Johannes A., Venter, Chantelle, Roberts, Timothy J., Tarr, Gareth, Kell, Douglas B., Pretorius, Etheresia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793985/
https://ncbi.nlm.nih.gov/pubmed/33424834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.577523
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