Vi-Vaccinations Induce Heterogeneous Plasma Cell Responses That Associate With Protection From Typhoid Fever

Vi-polysaccharide conjugate vaccines are efficacious against cases of typhoid fever; however, an absolute correlate of protection is not established. In this study, we investigated the leukocyte response to a Vi-tetanus toxoid conjugate vaccine (Vi-TT) in comparison with a plain polysaccharide vacci...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Cross, Deborah L., Verheul, Marije K., Leipold, Michael D., Obermoser, Gerlinde, Jin, Celina, Jones, Elizabeth, Starr, Joshua S., Mohorianu, Irina, Blohmke, Christoph J., Maecker, Holden T., Napolitani, Giorgio, Hill, Jennifer, Pollard, Andrew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793947/
https://ncbi.nlm.nih.gov/pubmed/33424833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.574057
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