Extracellular Citrate Fuels Cancer Cell Metabolism and Growth

Cancer cells need excess energy and essential nutrients/metabolites not only to divide and proliferate but also to migrate and invade distant organs for metastasis. Fatty acid and cholesterol synthesis, considered a hallmark of cancer for anabolism and membrane biogenesis, requires citrate. We revie...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Autores principales: Haferkamp, Sebastian, Drexler, Konstantin, Federlin, Marianne, Schlitt, Hans J., Berneburg, Mark, Adamski, Jerzy, Gaumann, Andreas, Geissler, Edward K., Ganapathy, Vadivel, Parkinson, E. Kenneth, Mycielska, Maria E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793864/
https://ncbi.nlm.nih.gov/pubmed/33425906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.602476
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