Evaluating the association of single-nucleotide polymorphisms with tenofovir exposure in a diverse prospective cohort of women living with HIV

Higher exposure to tenofovir (TFV) increases the risk for kidney function decline, but the impact of genetic factors on TFV exposure is largely unknown. We investigated whether single-nucleotide polymorphisms (SNPs, n = 211) in 12 genes are potentially involved in TFV exposure. Participants (n = 91)...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Baxi, SM, Greenblatt, RM, Bacchetti, P, Cohen, M, DeHovitz, JA, Anastos, K, Gange, SJ, Young, MA, Aouizerat, BE
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793629/
https://ncbi.nlm.nih.gov/pubmed/28462920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2017.3
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