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Pathogenic Impacts of Dysregulated Polycomb Repressive Complex Function in Hematological Malignancies
Polycomb repressive complexes (PRCs) are epigenetic regulators that mediate repressive histone modifications. PRCs play a pivotal role in the maintenance of hematopoietic stem cells through repression of target genes involved in cell proliferation and differentiation. Next-generation sequencing tech...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793497/ https://ncbi.nlm.nih.gov/pubmed/33374737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010074 |
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