Genomic analysis of mutations in platelet mitochondria in a case of benzene-induced leukaemia: A case report

INTRODUCTION: As a hematopoietic carcinogen, benzene induces human leukemia through its active metabolites such as benzoquinone, which may cause oxidative damage to cancer-related nuclear genes by increasing reactive oxygen species (ROS). Mitochondrion is the main regulatory organelle of ROS, geneti...

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Опубликовано в: :Medicine (Baltimore)
Главные авторы: Wang, Dianpeng, Yang, Xiangli, Cai, Diya, Li, Peimao, Zhang, Zhimin, Lin, Dafeng, Zhang, Yanfang
Формат: Artigo
Язык:Inglês
Опубликовано: Lippincott Williams & Wilkins 2021
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3500
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793417/
https://ncbi.nlm.nih.gov/pubmed/33429764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000024014
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