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Convergent evolution of diverse Bacillus anthracis outbreak strains toward altered surface oligosaccharides that modulate anthrax pathogenesis

Bacillus anthracis, a spore-forming gram-positive bacterium, causes anthrax. The external surface of the exosporium is coated with glycosylated proteins. The sugar additions are capped with the unique monosaccharide anthrose. The West African Group (WAG) B. anthracis have mutations rendering them an...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Norris, Michael H., Kirpich, Alexander, Bluhm, Andrew P., Zincke, Diansy, Hadfield, Ted, Ponciano, Jose Miguel, Blackburn, Jason K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7793302/
https://ncbi.nlm.nih.gov/pubmed/33370274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001052
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