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Co-impairment of autonomic and glucagon responses to insulin-induced hypoglycemia in dogs with naturally occurring insulin-dependent diabetes mellitus

This study aimed to investigate the contributions of two factors potentially impairing glucagon response to insulin-induced hypoglycemia (IIH) in insulin-deficient diabetes: 1) loss of paracrine disinhibition by intra-islet insulin and 2) defects in the activation of the autonomic inputs to the isle...

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Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Gilor, Chen, Duesberg, Cynthia, Elliott, Denise A., Feldman, Edward C., Mundinger, Thomas O., Taborsky, Gerald J., Nelson, Richard W., Havel, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792666/
https://ncbi.nlm.nih.gov/pubmed/33044845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00379.2020
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