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Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families

Background: The muscarinic receptor antagonist trospium chloride (TCl) is used for pharmacotherapy of the overactive bladder syndrome. TCl is a hydrophilic positively charged drug. Therefore, it has low permeability through biomembranes and requires drug transporters for distribution and excretion....

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發表在:Int J Mol Sci
Main Authors: Gorecki, Matthias, Müller, Simon F., Leidolf, Regina, Geyer, Joachim
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792585/
https://ncbi.nlm.nih.gov/pubmed/33375004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010022
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