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Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging

The process of aging and circadian rhythms are intimately intertwined, but how peripheral clocks involved in metabolic homeostasis contribute to aging remains unknown. Importantly, caloric restriction (CR) extends lifespan in several organisms and rewires circadian metabolism. Using young versus old...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Sato, Shogo, Solanas, Guiomar, Peixoto, Francisca Oliveira, Bee, Leonardo, Symeonidi, Aikaterini, Schmidt, Mark S., Brenner, Charles, Masri, Selma, Benitah, Salvador Aznar, Sassone-Corsi, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792549/
https://ncbi.nlm.nih.gov/pubmed/28802039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.042
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