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Human umbilical cord mesenchymal stem cell-derived exosomal miR-27b attenuates subretinal fibrosis via suppressing epithelial–mesenchymal transition by targeting HOXC6

BACKGROUND AND AIM: Subretinal fibrosis resulting from neovascular age-related macular degeneration (nAMD) is one of the major causes of serious and irreversible vision loss worldwide, and no definite and effective treatment exists currently. Retinal pigmented epithelium (RPE) cells are crucial in m...

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Dades bibliogràfiques
Publicat a:Stem Cell Res Ther
Autors principals: Li, Dongli, Zhang, Junxiu, Liu, Zijia, Gong, Yuanyuan, Zheng, Zhi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792361/
https://ncbi.nlm.nih.gov/pubmed/33413548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02064-0
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