Associations of Alzheimer’s disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration

BACKGROUND: Genome-wide association studies have identified more than 30 Alzheimer’s disease (AD) risk genes, although the detailed mechanism through which all these genes are associated with AD pathogenesis remains unknown. We comprehensively evaluate the roles of the variants in top 30 non-APOE AD...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Tan, Meng-Shan, Yang, Yu-Xiang, Xu, Wei, Wang, Hui-Fu, Tan, Lin, Zuo, Chuan-Tao, Dong, Qiang, Tan, Lan, Suckling, John, Yu, Jin-Tai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792349/
https://ncbi.nlm.nih.gov/pubmed/33419465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00755-7
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