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Increased Glucose Availability Attenuates Myocardial Ketone Body Utilization

BACKGROUND: Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects. The failing heart in nondiabetics tends to decrease reliance on fatty acid and glucose oxidation, and increases reliance on ketone body oxid...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Brahma, Manoja K., Ha, Chae‐Myeong, Pepin, Mark E., Mia, Sobuj, Sun, Zhihuan, Chatham, John C., Habegger, Kirk M., Abel, Evan Dale, Paterson, Andrew J., Young, Martin E., Wende, Adam R.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792234/
https://ncbi.nlm.nih.gov/pubmed/32750298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.013039
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