Quantifying the effects of biopsy fixation and staining panel design on automatic instance segmentation of immune cells in human lupus nephritis

Significance: Lupus nephritis (LuN) is a chronic inflammatory kidney disease. The cellular mechanisms by which LuN progresses to kidney failure are poorly characterized. Automated instance segmentation of immune cells in immunofluorescence images of LuN can probe these cellular interactions. Aim: Ou...

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Bibliografiske detaljer
Udgivet i:J Biomed Opt
Main Authors: Durkee, Madeleine S., Abraham, Rebecca, Ai, Junting, Veselits, Margaret, Clark, Marcus R., Giger, Maryellen L.
Format: Artigo
Sprog:Inglês
Udgivet: Society of Photo-Optical Instrumentation Engineers 2021
Fag:
Special Series on Artificial Intelligence and Machine Learning in Biomedical Optics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791891/
https://ncbi.nlm.nih.gov/pubmed/33420765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.26.2.022910
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