Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells

BACKGROUND: Anterior gradient-2 (AGR2) is a proto-oncogene involved in tumorigenesis and cancer progression. AGR2, predominantly localized in the endoplasmic reticulum (ER), is also a secreted protein detected in the extracellular compartment in multiple cancers. However, the biological functions of...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Hong, Xian, Li, Zhi-Xuan, Hou, Jie, Zhang, Hui-Yu, Zhang, Chun-Yan, Zhang, Jian, Sun, He, Pang, Li-Hong, Wang, Tao, Deng, Zhi-Hui
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791724/
https://ncbi.nlm.nih.gov/pubmed/33413231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07743-y
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