Failure to maintain full-term pregnancies in pig carrying klotho monoallelic knockout fetuses

BACKGROUND: Small animals that show a deficiency in klotho exhibit extremely shortened life span with multiple aging-like phenotypes. However, limited information is available on the function of klotho in large animals such as pigs. RESULTS: In an attempt to produce klotho knockout pigs, an sgRNA sp...

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Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Lee, Sanghoon, Jung, Min Hee, Song, Kilyoung, Jin, Jun-Xue, Taweechaipaisankul, Anukul, Kim, Geon A., Oh, Hyun Ju, Koo, Ok Jae, Park, Se Chang, Lee, Byeong Chun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791653/
https://ncbi.nlm.nih.gov/pubmed/33413301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-020-00660-9
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