CYP2J2 promotes the development of hepatocellular carcinoma by increasing the EETs production to improve HIF-1α stability

Objective: This study aimed to explore the function and mechanism of Cytochrome P450 2J2 (CYP2J2) epoxygenase and epoxyeicosatrienoic acids (EETs) in the malignant development of hepatocellular carcinoma (HCC). Method: The expressional levels of EETs and CYP2J2 in HCC tissues and cell lines were qua...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Gui, Liang, Xu, Qiang, Huang, Juju, Wu, Gaojue, Tang, Hong, Hui, Li, Hua, Ping, Zhang, Lili, Zhu, Yingwei
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2020
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791520/
https://ncbi.nlm.nih.gov/pubmed/33437370
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