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Deficiency of Plasminogen Activator Inhibitor-2 Results in Accelerated Tumor Growth
BACKGROUND: Upregulation of the plasminogen activation system, including urokinase plasminogen activator (uPA), has been observed in many malignancies, suggesting that co-opting the PA system is a common method by which tumor cells accomplish extracellular matrix proteolysis. PAI-2, a serine proteas...
Sparad:
I publikationen: | J Thromb Haemost |
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Huvudupphovsmän: | , , , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2020
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7791406/ https://ncbi.nlm.nih.gov/pubmed/32780555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15054 |
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