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Deficiency of Plasminogen Activator Inhibitor-2 Results in Accelerated Tumor Growth

BACKGROUND: Upregulation of the plasminogen activation system, including urokinase plasminogen activator (uPA), has been observed in many malignancies, suggesting that co-opting the PA system is a common method by which tumor cells accomplish extracellular matrix proteolysis. PAI-2, a serine proteas...

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Bibliografiska uppgifter
I publikationen:J Thromb Haemost
Huvudupphovsmän: Westrick, Randal J., Røjkjær, Lisa Payne, Yang, Angela Y., Roh, Michael H., Siebert, Amy E., Ginsburg, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791406/
https://ncbi.nlm.nih.gov/pubmed/32780555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15054
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