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MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway

MIEF2 (mitochondrial elongation factor 2) is one of the key regulators of mitochondrial fission. Bioinformatics analysis indicated that high expression of MIEF2 predicted a poor prognosis in ovarian cancer patients. However, the relationship between MIEF2 and aberrant lipid metabolism in OC remains...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Zhao, Shuhua, Cheng, Lu, Shi, Yuan, Li, Jia, Yun, Qinghui, Yang, Hong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791105/
https://ncbi.nlm.nih.gov/pubmed/33414447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03336-6
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