CRISPR-Cas9-Edited Tacrolimus-Resistant Antiviral T Cells for Advanced Adoptive Immunotherapy in Transplant Recipients

Viral infections, such as with cytomegalovirus (CMV), remain a major risk factor for mortality and morbidity of transplant recipients because of their requirement for lifelong immunosuppression (IS). Antiviral drugs often cause toxicity and sometimes fail to control disease. Thus, regeneration of th...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther
Egile Nagusiak: Amini, Leila, Wagner, Dimitrios Laurin, Rössler, Uta, Zarrinrad, Ghazaleh, Wagner, Livia Felicitas, Vollmer, Tino, Wendering, Désirée Jacqueline, Kornak, Uwe, Volk, Hans-Dieter, Reinke, Petra, Schmueck-Henneresse, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2021
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791012/
https://ncbi.nlm.nih.gov/pubmed/32956624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.09.011
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