Circular RNA circPDE4D Protects against Osteoarthritis by Binding to miR-103a-3p and Regulating FGF18

Osteoarthritis (OA) is a common, age-related, and painful disease characterized by cartilage destruction, osteophyte formation, and synovial hyperplasia. This study revealed that circPDE4D, a circular RNA derived from human linear PDE4D, plays a critical role in maintaining the extracellular cellula...

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Dades bibliogràfiques
Publicat a:Mol Ther
Autors principals: Wu, Yizheng, Hong, Zhenghua, Xu, Wenbin, Chen, Junxin, Wang, Qingxin, Chen, Jiaxin, Ni, Weiyu, Mei, Zixuan, Xie, Ziang, Ma, Yan, Wang, Jiying, Lu, Jianhong, Chen, Chao, Fan, Shunwu, Shen, Shuying
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2021
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791010/
https://ncbi.nlm.nih.gov/pubmed/33125858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.09.002
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