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Estrogen receptor-α signaling increases allergen-induced IL-33 release and airway inflammation
BACKGROUND: Group 2 innate lymphoid cells (ILC2) are stimulated by IL-33 to increase IL-5 and IL-13 production and airway inflammation. While sex hormones regulate airway inflammation, it remained unclear if estrogen signaling through estrogen receptor-α (ER-α, Esr1) or ER-β (Esr2) increased ILC2-me...
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| Publicado no: | Allergy |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7790897/ https://ncbi.nlm.nih.gov/pubmed/32648964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14491 |
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