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Development of New Tuberculosis Drugs: Translation to Regimen Composition for Drug-Sensitive and Multidrug-Resistant Tuberculosis

Tuberculosis (TB) kills more people than any other infectious disease. Challenges for developing better treatments include the complex pathology due to within-host immune dynamics, interpatient variability in disease severity and drug pharmacokinetics-pharmacodynamics (PK-PD), and the growing emerge...

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Detalhes bibliográficos
Publicado no:Annu Rev Pharmacol Toxicol
Main Authors: Ernest, Jacqueline P., Strydom, Natasha, Wang, Qianwen, Zhang, Nan, Nuermberger, Eric, Dartois, Véronique, Savic, Rada M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790895/
https://ncbi.nlm.nih.gov/pubmed/32806997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-030920-011143
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