eNOS-dependent S-nitrosylation of the NF-κB subunit p65 has neuroprotective effects

Cell death by glutamate excitotoxicity, mediated by N-methyl-d-aspartate (NMDA) receptors, negatively impacts brain function, including but not limited to hippocampal neurons. The NF-κB transcription factor (composed mainly of p65/p50 subunits) contributes to neuronal death in excitotoxicity, while...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Caviedes, Ariel, Maturana, Barbara, Corvalán, Katherina, Engler, Alexander, Gordillo, Felipe, Varas-Godoy, Manuel, Smalla, Karl-Heinz, Batiz, Luis Federico, Lafourcade, Carlos, Kaehne, Thilo, Wyneken, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790835/
https://ncbi.nlm.nih.gov/pubmed/33414434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03338-4
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