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Cross-talk between Hippo and Wnt signalling pathways in intestinal crypts: Insights from an agent-based model

Intestinal crypts are responsible for the total cell renewal of the lining of the intestines; this turnover is governed by the interplay between signalling pathways and the cell cycle. The role of Wnt signalling in cell proliferation and differentiation in the intestinal crypt has been extensively s...

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Pubblicato in:Comput Struct Biotechnol J
Autori principali: Ward, Daniel, Montes Olivas, Sandra, Fletcher, Alexander, Homer, Martin, Marucci, Lucia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790739/
https://ncbi.nlm.nih.gov/pubmed/33489001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.12.015
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