Nanovaccine administration route is critical to obtain pertinent iNKt cell help for robust anti-tumor T and B cell responses

Nanovaccines, co-delivering antigen and invariant natural killer T (iNKT) cell agonists, proved to be very effective in inducing anti-tumor T cell responses due to their exceptional helper function. However, it is known that iNKT cells are not equally present in all lymphoid organs and nanoparticles...

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Veröffentlicht in:Oncoimmunology
Hauptverfasser: Dölen, Yusuf, Valente, Michael, Tagit, Oya, Jäger, Eliezer, Van Dinther, Eric A. W., van Riessen, N. Koen, Hruby, Martin, Gileadi, Uzi, Cerundolo, Vincenzo, Figdor, Carl G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
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Back Matter
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790498/
https://ncbi.nlm.nih.gov/pubmed/33457086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1738813
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