Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis

Two component systems (TCSs) are a primary mechanism of signal sensing and response in bacteria. Systematic characterization of an entire TCS could provide a mechanistic understanding of these important signal transduction systems. Here, genetic selections were employed to dissect the molecular basi...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Pi, Hualiang, Chu, Michelle L., Ivan, Samuel J., Latario, Casey J., Toth, Allen M., Carlin, Sophia M., Hillebrand, Gideon H., Lin, Hannah K., Reppart, Jared D., Stauff, Devin L., Skaar, Eric P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790381/
https://ncbi.nlm.nih.gov/pubmed/33362282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009148
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