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Alveolar CCN1 is associated with mechanical stretch and acute respiratory distress syndrome severity

The cellular communication network factor 1 (CCN1) is a matricellular protein that can modulate multiple tissue responses, including inflammation and repair. We have previously shown that adenoviral overexpression of Ccn1 is sufficient to cause acute lung injury in mice. We hypothesized that CCN1 is...

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Detalles Bibliográficos
Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Morrell, Eric D., Grazioli, Serge, Hung, Chi, Kajikawa, Osamu, Kosamo, Susanna, Stapleton, Renee D., Gharib, Sina A., Amado-Rodríguez, Laura, Albaiceta, Guillermo, Wurfel, Mark M., Matute-Bello, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789974/
https://ncbi.nlm.nih.gov/pubmed/32936024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00073.2020
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