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Computational analysis to repurpose drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2

BACKGROUND: The Coronavirus Disease 2019 (COVID-19) pandemic has infected over 10 million people globally with a relatively high mortality rate. There are many therapeutics undergoing clinical trials, but there is no effective vaccine or therapy for treatment thus far. After affected by the Severe A...

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Pubblicato in:BMC Med Inform Decis Mak
Autori principali: Li, Fuhai, Michelson, Andrew P., Foraker, Randi, Zhan, Ming, Payne, Philip R. O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789899/
https://ncbi.nlm.nih.gov/pubmed/33413329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-020-01373-x
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