ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity

Resistances to immunotherapies remains a major hurdle towards a cure for melanoma in numerous patients. An increase in the mesenchymal phenotype and a loss of differentiation have been clearly associated with resistance to targeted therapies. Similar phenotypes have been more recently also linked to...

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Vydáno v:Mol Cancer
Hlavní autoři: Cheli, Yann, Tulic, Meri K., El Hachem, Najla, Nottet, Nicolas, Jacquel, Arnaud, Gesson, Maeva, Strub, Thomas, Bille, Karine, Picard-Gauci, Alexandra, Montaudié, Henri, Beranger, Guillaume E., Passeron, Thierry, Close, Pierre, Bertolotto, Corine, Ballotti, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Letter to the Editor
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789764/
https://ncbi.nlm.nih.gov/pubmed/33413419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01306-2
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