Hypoxic hUCMSC-derived extracellular vesicles attenuate allergic airway inflammation and airway remodeling in chronic asthma mice

BACKGROUND: As one of the main functional forms of mesenchymal stem cells (MSCs), MSC-derived extracellular vesicles (MSC-EVs) have shown an alternative therapeutic option in experimental models of allergic asthma. Oxygen concentration plays an important role in the self-renewal, proliferation, and...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Dong, Liyang, Wang, Ying, Zheng, Tingting, Pu, Yanan, Ma, Yongbin, Qi, Xin, Zhang, Wenzhe, Xue, Fei, Shan, Zirui, Liu, Jiameng, Wang, Xuefeng, Mao, Chaoming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789736/
https://ncbi.nlm.nih.gov/pubmed/33407872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02072-0
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