Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model

BACKGROUND: Both genetic factors and environmental hazards, including environmental noise stress, have been associated with gut microbiome that exacerbates Alzheimer’s disease (AD) pathology. However, the role and mechanism of environmental risk factors in early-onset AD (EOAD) pathogenesis remain u...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Chi, Huimin, Cao, Wa, Zhang, Ming, Su, Donghong, Yang, Honglian, Li, Zhe, Li, Chao, She, Xiaojun, Wang, Kun, Gao, Xiujie, Ma, Kefeng, Zheng, Pengfang, Li, Xiaofang, Cui, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789697/
https://ncbi.nlm.nih.gov/pubmed/33407614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02053-3
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