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Targeting the IL-5 pathway in eosinophilic asthma: a comparison of mepolizumab to benralizumab in the reduction of peripheral eosinophil counts

BACKGROUND: Mepolizumab and benralizumab are biologics approved for severe eosinophilic asthma. Mepolizumab is an anti-interlukin-5 (IL-5) antibody while benralizumab is an anti-interleukin-5 receptor alpha (IL-5Rα) antibody targeting the IL-5 receptor on eosinophils. Both therapies reduce oral cort...

詳細記述

保存先:
書誌詳細
出版年:Allergy Asthma Clin Immunol
主要な著者: Ghassemian, Arian, Park, Jane Jiyoon, Tsoulis, Michael W., Kim, Harold
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789431/
https://ncbi.nlm.nih.gov/pubmed/33407869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13223-020-00507-0
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