Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients

BACKGROUND: KRAS gene is the most common type of mutation reported in colorectal cancer (CRC). KRAS mutation-mediated regulation of immunophenotype and immune pathways in CRC remains to be elucidated. METHODS: 535 CRC patients were used to compare the expression of immune-related genes (IRGs) and th...

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Bibliografiske detaljer
Udgivet i:J Transl Med
Main Authors: Liu, Jungang, Huang, Xiaoliang, Liu, Haizhou, Wei, Chunyin, Ru, Haiming, Qin, Haiquan, Lai, Hao, Meng, Yongsheng, Wu, Guo, Xie, Weishun, Mo, Xianwei, Johnson, Caroline H., Zhang, Yawei, Tang, Weizhong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789428/
https://ncbi.nlm.nih.gov/pubmed/33413474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02638-9
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