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MicroRNA-223-induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways

The tumour suppressor gene F-box and WD repeat domain-containing 7 (FBXW7) plays an important role in human cancer by regulating cell division, proliferation and differentiation. However, the exact regulatory mechanisms of microRNA (miR)-223 in colorectal cancer (CRC) cells are still unknown. The pr...

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Publicado en:Mol Med Rep
Autores principales: Liu, Zhixin, Ma, Teng, Duan, Jufeng, Liu, Xiaofei, Liu, Long
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789109/
https://ncbi.nlm.nih.gov/pubmed/33355365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11793
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