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Promotion of epithelial-mesenchymal transformation by hepatocellular carcinoma-educated macrophages through Wnt2b/β-catenin/c-Myc signaling and reprogramming glycolysis

BACKGROUND: Tumour-associated macrophages (TAMs) in the tumour microenvironment (TME) can promote the progression of hepatocellular carcinoma (HCC). Some tumours can be suppressed by targeting Wnt2b in tumour cells. However, the role of Wnt2b in HCC is still unknown. In particular, the role of Wnt2b...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Jiang, Yu, Han, Qiuju, Zhao, Huajun, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788901/
https://ncbi.nlm.nih.gov/pubmed/33407720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01808-3
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