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Direct comparison of 3D and 2D cultivation reveals higher osteogenic capacity of elderly osteoblasts in 3D

BACKGROUND: The aim of this study was the investigation of the osteogenic potential of human osteoblasts of advanced donor age in 2D and 3D culture. METHODS: Osteoblasts were induced to osteogenic differentiation and cultivated, using the same polystyrene material in 2D and 3D culture for 2 weeks. S...

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Vydáno v:J Orthop Surg Res
Hlavní autoři: Payr, Stephan, Rosado-Balmayor, Elizabeth, Tiefenboeck, Thomas, Schuseil, Tim, Unger, Marina, Seeliger, Claudine, van Griensven, Martijn
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788858/
https://ncbi.nlm.nih.gov/pubmed/33407623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-020-02153-z
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