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Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high dosage of dexamethasone

BACKGROUND: Abnormalities in apoptosis, cell cycle, proliferation, and differentiation of human bone marrow mesenchymal stem cells (hBMSCs) significantly impact bone metabolism and remodeling, resulting in various skeletal disorders. Long-term exposure to a high dosage of dexamethasone (Dex) induces...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Li, Tao, Xu, Yingxing, Wang, Yingzhen, Jiang, Yaping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788840/
https://ncbi.nlm.nih.gov/pubmed/33407832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02040-8
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