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Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury

BACKGROUND: The acute phase response (APR) to CNS insults contributes to the overall magnitude and nature of the systemic inflammatory response. Aspects of this response are thought to drive secondary inflammatory pathology at the lesion site, and suppression of the APR can therefore afford some neu...

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Publicado en:J Neuroinflammation
Autores principales: Yates, Abi G., Jogia, Trisha, Gillespie, Ellen R., Couch, Yvonne, Ruitenberg, Marc J., Anthony, Daniel C.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788822/
https://ncbi.nlm.nih.gov/pubmed/33407641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02050-6
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