PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway

BACKGROUND: Angiogenic placental growth factor (PlGF) plays a role in hypoxia-induced angiogenesis. Here, we aimed to investigate the biological roles of PlGF in cell proliferation and glycolysis of lung adenocarcinoma (LUAD) and the underlying molecular mechanisms. METHODS: PlGF was knocked down in...

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Publicat a:Cancer Cell Int
Autors principals: Zhang, Wei, Zhang, Yanwei, Zhou, Wensheng, Qian, Fangfei, Hu, Minjuan, Chen, Ya, Lu, Jun, Lou, Yuqing, Han, Baohui
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788771/
https://ncbi.nlm.nih.gov/pubmed/33407494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01714-w
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