The Effects of Tofacitinib-Mediated Janus Kinase/Signal Transducers and Activators of the Transcription Signal Pathway Inhibition on Collagen Biosynthesis in Hepatic and Skin Fibroblast Cell Culture

OBJECTIVES: This study aims to investigate the effects of Janus kinase/signal transducers and activators of the transcription (JAK/STAT) pathway inhibition on collagen biosynthesis in fibroblast cell culture by tofacitinib. MATERIALS AND METHODS: BJ-CRL-1474® (skin) and BRL3A® (hepatic) fibroblast c...

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Enregistré dans:
Détails bibliographiques
Publié dans:Arch Rheumatol
Auteurs principaux: ŞAHİN, Mehtap, AYDIN, Hüseyin, ALTUN, Ahmet, DERİN, Mehmet Emin, ŞAHİN, Ali
Format: Artigo
Langue:Inglês
Publié: Turkish League Against Rheumatism 2020
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788643/
https://ncbi.nlm.nih.gov/pubmed/33458657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.46497/ArchRheumatol.2020.7568
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