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Isolation and culture of mouse alveolar type II cells to study type II to type I cell differentiation

Alveolar type II cells (AT2) are stem cells of lung epithelium. To study these cells, we developed protocols to isolate primary AT2 and test the effects of potential niche factors in regulating the AT2 progenitor functions. AT2 freshly isolated from mouse lungs are grown in 2D or 3D culture. AT2 are...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Chen, Qian, Liu, Yuru
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788236/
https://ncbi.nlm.nih.gov/pubmed/33437966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100241
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