Subcutaneous Injection Performance in Yucatan Miniature Pigs with and without Human Hyaluronidase and Auto-injector Tolerability in Humans

Recombinant human hyaluronidase PH20 (rHuPH20) facilitates subcutaneous (SC) delivery of co-administered therapeutic agents by locally and transiently degrading hyaluronan in the SC space, and can be administered with therapeutics using a variety of devices. Two SC delivery studies were carried out...

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Bibliographic Details
Published in:AAPS PharmSciTech
Main Authors: Shi, Galen H., Connor, Robert J., Collins, David S., Kang, David W.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788039/
https://ncbi.nlm.nih.gov/pubmed/33409604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-020-01880-0
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