Exosomes Derived from Human Urine-Derived Stem Cells Inhibit Intervertebral Disc Degeneration by Ameliorating Endoplasmic Reticulum Stress

OBJECTIVE: This study is aimed at determining the effects of human urine-derived stem cell-derived exosomes (USCs-exos) on pressure-induced nucleus pulposus cell (NPC) apoptosis and intervertebral disc degeneration (IDD) and on the ERK and AKT signaling pathways. METHODS: The NPCs were obtained from...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Xiang, HongFei, Su, WeiLiang, Wu, XiaoLin, Chen, WuJun, Cong, WenBin, Yang, Shuai, Liu, Chang, Qiu, ChenSheng, Yang, Shang-You, Wang, Yan, Zhang, GuoQing, Guo, Zhu, Xing, DongMing, Chen, BoHua
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787770/
https://ncbi.nlm.nih.gov/pubmed/33488928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6697577
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