IL-33 facilitates rapid expulsion of the parasitic nematode Strongyloides ratti from the intestine via ILC2- and IL-9-driven mast cell activation

Parasitic helminths are sensed by the immune system via tissue-derived alarmins that promote the initiation of the appropriate type 2 immune responses. Here we establish the nuclear alarmin cytokine IL-33 as a non-redundant trigger of specifically IL-9-driven and mast cell-mediated immunity to the i...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Meiners, Jana, Reitz, Martina, Rüdiger, Nikolas, Turner, Jan-Eric, Heepmann, Lennart, Rudolf, Lena, Hartmann, Wiebke, McSorley, Henry J., Breloer, Minka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787685/
https://ncbi.nlm.nih.gov/pubmed/33351862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009121
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