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Burden of rare exome sequence variants in PROC gene is associated with venous thromboembolism: a population-based study

BACKGROUND: Rare coding mutations underlying deficiencies of antithrombin and proteins C and S contribute to familial venous thromboembolism (VTE). It is uncertain whether rare variants play a role in the etiology of VTE in the general population. OBJECTIVES: We conducted a deep whole-exome sequenci...

詳細記述

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書誌詳細
出版年:J Thromb Haemost
主要な著者: Tang, Weihong, Stimson, Mary Rachel, Basu, Saonli, Heckbert, Susan R., Cushman, Mary, Pankow, James S., Folsom, Aaron R., Pankratz, Nathan
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787541/
https://ncbi.nlm.nih.gov/pubmed/31680443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14676
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