Differentiating axonal loss and demyelination in chronic MS lesions: A novel approach using single streamline diffusivity analysis

We describe a new single-streamline based approach to analyse diffusivity within chronic MS lesions. We used the proposed method to examine diffusivity profiles in 30 patients with relapsing multiple sclerosis and observed a significant increase of both RD and AD within the lesion core (0.38+/-0.09...

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Bibliographic Details
Published in:PLoS One
Main Authors: Klistorner, Samuel, Barnett, Michael H., Wasserthal, Jakob, Yiannikas, Con, Barton, Joshua, Parratt, John, You, Yuyi, Graham, Stuart L., Klistorner, Alexander
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787472/
https://ncbi.nlm.nih.gov/pubmed/33406139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244766
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