MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species

Adjuvant chemotherapy for solid tumors based on platinum-derived compounds such as cisplatin is the treatment of choice in most cases. Cisplatin triggers signaling pathways that lead to cell death, but it also induces changes in tumor cells that modify the therapeutic response, thereby leading to ci...

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Pubblicato in:Transl Res
Autori principali: VERA-PUENTE, OLGA, RODRIGUEZ-ANTOLIN, CARLOS, SALGADO-FIGUEROA, ANA, MICHALSKA, PATRYCJA, PERNIA, OLGA, REID, BRETT M., ROSAS, ROCÍO, GARCIA-GUEDE, ALVARO, SACRISTÁN, SILVIA, JIMENEZ, JULIA, ESTEBAN-RODRIGUEZ, ISABEL, MARTIN, M. ELENA, SELLERS, THOMAS A., LEÓN, RAFAEL, GONZALEZ, VÍCTOR M., DE CASTRO, JAVIER, DE CACERES, INMACULADA IBANEZ
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787305/
https://ncbi.nlm.nih.gov/pubmed/30053382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2018.06.005
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