A conserved dendritic-cell regulatory program limits antitumour immunity

Checkpoint blockade therapies have improved cancer treatment, but such immunotherapy regimens fail in a large subset of patients. Conventional type 1 dendritic cells (DC1s) control the response to checkpoint blockade in preclinical models and are associated with better overall survival in patients w...

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Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Maier, Barbara, Leader, Andrew M., Chen, Steven T., Tung, Navpreet, Chang, Christie, LeBerichel, Jessica, Chudnovskiy, Aleksey, Maskey, Shrisha, Walker, Laura, Finnigan, John P., Kirkling, Margaret E., Reizis, Boris, Ghosh, Sourav, D’Amore, Natalie Roy, Bhardwaj, Nina, Rothlin, Carla V., Wolf, Andrea, Flores, Raja, Marron, Thomas, Rahman, Adeeb H., Kenigsberg, Ephraim, Brown, Brian D., Merad, Miriam
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787191/
https://ncbi.nlm.nih.gov/pubmed/32269339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2134-y
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