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Inhibition of Cathepsin S Induces Mitochondrial Apoptosis in Glioblastoma Cell Lines Through Mitochondrial Stress and Autophagosome Accumulation

Cathepsin S (CTSS), a lysosomal cysteine protease, is overexpressed in various cancers, including glioblastoma (GB). A high level of CTSS is associated with tumor progression and poor outcome in GB. However, the underlying mechanisms of its role in the biological characteristics of G5B remain to be...

詳細記述

保存先:
書誌詳細
出版年:Front Oncol
主要な著者: Fei, Maoxing, Zhang, Li, Wang, Handong, Zhu, Yihao, Niu, Wenhao, Tang, Ting, Han, Yanling
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787074/
https://ncbi.nlm.nih.gov/pubmed/33425712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.516746
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